Iho1 Gene Summary [Mouse]
Involved in several processes, including meiosis I cell cycle process; regulation of homologous chromosome segregation; and spermatogenesis. Located in condensed nuclear chromosome. Is expressed in alimentary system; central nervous system; lung; temporal bone petrous part; and testis. Orthologous to human IHO1 (interactor of HORMAD1 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Iho1 |
| Official Name | interactor of HORMAD1 1 [Source:MGI Symbol;Acc:MGI:3612242] |
| Ensembl ID | ENSMUSG00000047220 |
| Bio databases IDs | |
| Aliases | interactor of HORMAD1 1 |
| Synonyms | CCDC36, CT74, interactor of HORMAD1 1, LELA1, LOC339834, LOC686631 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Iho1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Interactor of HORMAD1 protein 1
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Iho1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of homologous chromosome segregation
- oogenesis
- spermatogenesis
- DNA recombination
- synapsis
- meiotic DNA double-strand break formation
Cellular Component
Where in the cell the gene product is active
- condensed nuclear chromosome
Molecular Function
What the gene product does at the molecular level
- protein binding