IHO1 Gene Summary [Human]

Predicted to be involved in gamete generation; meiosis I cell cycle process; and regulation of homologous chromosome segregation. Predicted to be active in condensed nuclear chromosome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
IHO1
Official Name
interactor of HORMAD1 1 [Source:HGNC Symbol;Acc:HGNC:27945]
Ensembl ID
ENSG00000173421
Bio databases IDs NCBI: 339834 Ensembl: ENSG00000173421
Aliases interactor of HORMAD1 1, cancer/testis antigen 74
Synonyms CCDC36, CT74, interactor of HORMAD1 1, LELA1, LOC339834, LOC686631
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IHO1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Interactor of HORMAD1 protein 1
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • depressive disorder
  • insomnia
  • anxiety disorder
regulated by
  • MIR486
  • MEIOSIN/STRA8
  • estradiol-17beta-benzoate
role in cell
  • formation
  • abnormal morphology
  • synapsis in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • chromosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human IHO1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of homologous chromosome segregation
  • oogenesis
  • spermatogenesis
  • DNA recombination
  • synapsis
  • meiotic DNA double-strand break formation

Cellular Component

Where in the cell the gene product is active
  • condensed nuclear chromosome

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.