Coa7

Predicted to enable protein-disulfide reductase activity. Predicted to be involved in respiratory chain complex IV assembly. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in spinocerebellar ataxia with axonal neuropathy type 3. Orthologous to human COA7 (cytochrome c oxidase assembly factor 7). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Coa7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Coa7 gene, providing context for its role in the cell.