Gpr137c Gene Summary [Mouse]

Predicted to be involved in positive regulation of TORC1 signaling. Predicted to be active in lysosomal membrane. Orthologous to human GPR137C (G protein-coupled receptor 137C). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Gpr137c
Official Name
G protein-coupled receptor 137C [Source:MGI Symbol;Acc:MGI:1917963]
Ensembl ID
ENSMUSG00000049092
Bio databases IDs NCBI: 70713 Ensembl: ENSMUSG00000049092
Aliases G protein-coupled receptor 137C
Synonyms 6330416L11Rik, Gm908, G protein-coupled receptor 137C, LOC100041611, LOC684928, RGD1563070, TM7SF1L2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr137c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Gpr137c gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • small cell lung cancer
  • myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
  • peripheral arterial disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • lysosome membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr137c gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • lysosomal membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.