Omg Gene Summary [Mouse]

Enables identical protein binding activity. Acts upstream of or within neuron projection regeneration and regulation of collateral sprouting of intact axon in response to injury. Predicted to be located in myelin sheath and plasma membrane. Is expressed in brain and spinal cord. Orthologous to human OMG (oligodendrocyte myelin glycoprotein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Omg
Official Name
oligodendrocyte myelin glycoprotein [Source:MGI Symbol;Acc:MGI:106586]
Ensembl ID
ENSMUSG00000049612
Bio databases IDs NCBI: 18377 Ensembl: ENSMUSG00000049612
Aliases oligodendrocyte myelin glycoprotein
Synonyms oligodendrocyte-myelin glycoprotein, OMGP
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Omg often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • Leucine-rich repeats, outliers
  • Leucine-rich repeats, typical (most populated) subfamily
  • leucine-rich repeat
  • protein phosphatase 1 regulatory subunit 42
  • ectodomain
  • Leucine rich repeat
  • protein homodimerization
  • serine threonine rich domain
  • Leucine rich repeat N-terminal domain
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diverticular disease
regulated by
  • Influenza A virus (A/Bangkok/RX73(H3N2))
  • CREB1
  • beta-estradiol
  • medroxyprogesterone acetate
  • phytohemagglutinin
  • SORL1
  • BDNF
  • RTN4R
regulates
role in cell
  • growth
  • length
  • outgrowth
  • G1 phase
  • long-term potentiation in
  • elongation
  • regeneration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • cellular membrane
  • myelin sheath

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Omg gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuron projection regeneration
  • cell adhesion

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

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