Krt78 Gene Summary [Mouse]
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Is active in cornified envelope. Orthologous to human KRT78 (keratin 78). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt78 |
| Official Name | keratin 78 [Source:MGI Symbol;Acc:MGI:1917529] |
| Ensembl ID | ENSMUSG00000050463 |
| Bio databases IDs | |
| Aliases | keratin 78 |
| Synonyms | 2310030B04Rik, Kb40, keratin 78 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krt78 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nuf2, DHR10-like domain
- Rabaptin-like protein
- type III secretion apparatus protein, HrpE/YscL family
- TPR/MLP1/MLP2-like protein
- Autophagy protein ATG17-like domain
- Secreted virulence factor YukE/EsxA, WXG100 family [Defense mechanisms]
- Type III secretion protein YscO
- Effector-associated domain 9
- Spindle pole body component BBP1, C-terminal
- Mechanosensitive ion channel porin domain
- Proteins of 100 residues with WXG
- Intermediate filament protein
- Domain of unknown function (DUF4200)
Pathways
Biological processes and signaling networks where the Krt78 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cornified envelope