Gk2 Gene Summary [Mouse]
Predicted to enable glycerol kinase activity. Involved in sperm mitochondrial sheath assembly. Located in mitochondrial outer membrane and sperm mitochondrial sheath. Orthologous to human GK2 (glycerol kinase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gk2 |
| Official Name | glycerol kinase 2 [Source:MGI Symbol;Acc:MGI:1329027] |
| Ensembl ID | ENSMUSG00000050553 |
| Bio databases IDs | |
| Aliases | glycerol kinase 2 |
| Synonyms | GKP2, GK-RS2, GKTA, glycerol kinase 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gk2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- FGGY family of carbohydrate kinases, C-terminal domain
- glycerol kinase
- FGGY family of carbohydrate kinases, N-terminal domain
- protein binding
- ASKHA_ATPase-like
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
- sperm midpiece
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gk2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycerol metabolic process
- sperm motility
- glycerol-3-phosphate biosynthetic process
- spermatogenesis
- glycerol catabolic process
- triglyceride metabolic process
- phosphorylation
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- sperm midpiece
- mitochondrion
- sperm mitochondrial sheath
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- glycerol kinase activity