Tor1aip2 Gene Summary [Mouse]
Predicted to enable ATPase activator activity and ATPase binding activity. Predicted to be involved in several processes, including endoplasmic reticulum organization; positive regulation of ATP-dependent activity; and protein localization to nuclear envelope. Located in endoplasmic reticulum. Is expressed in several structures, including 1st branchial arch mandibular component mesenchyme; alimentary system; central nervous system; sensory organ; and skin. Orthologous to human TOR1AIP2 (torsin 1A interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tor1aip2 |
| Official Name | torsin A interacting protein 2 [Source:MGI Symbol;Acc:MGI:3582695] |
| Ensembl ID | ENSMUSG00000050565 |
| Bio databases IDs | |
| Aliases | torsin A interacting protein 2 |
| Synonyms | 1110020D10Rik, A130072J07, IFRG15, LOC163590, LULL1, NET9, torsin 1A interacting protein 2, torsin A interacting protein 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tor1aip2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATPase stimulator
- Mucin-like
- ATPase binding
- Lamina-associated polypeptide 1, AAA+ activator domain
- protein binding
- Lamina-associated polypeptide 1, N-terminal
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum mitochondria contact site
- Endoplasmic Reticulum
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tor1aip2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane organization
- positive regulation of ATPase activity
- endoplasmic reticulum organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nuclear membrane
- membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding
- ATPase activator activity
- ATPase binding