Marcks

Enables several functions, including actin filament binding activity; calmodulin binding activity; and protein kinase C binding activity. Involved in several processes, including actin filament organization; nervous system development; and response to endoplasmic reticulum stress. Located in several cellular components, including cell cortex; cytoskeleton; and germinal vesicle. Is active in organelle. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; nerve; and sensory organ. Human ortholog(s) of this gene implicated in Lynch syndrome. Orthologous to human MARCKS (myristoylated alanine rich protein kinase C substrate). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Marcks often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Marcks gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Marcks gene, providing context for its role in the cell.