Krt9 Gene Summary [Mouse]
Predicted to enable structural molecule activity. Involved in spermatogenesis. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in keratin filament. Is expressed in several structures, including alimentary system; gonad; hemolymphoid system gland; metanephros; and respiratory system. Human ortholog(s) of this gene implicated in epidermolytic palmoplantar keratoderma 1. Orthologous to human KRT9 (keratin 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt9 |
| Official Name | keratin 9 [Source:MGI Symbol;Acc:MGI:96696] |
| Ensembl ID | ENSMUSG00000051617 |
| Bio databases IDs | |
| Aliases | keratin 9 |
| Synonyms | CK-9, EPPK, EPPK1, K9, keratin 9, KRT1-9 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krt9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of cytoskeleton
- Intermediate filament protein
Pathways
Biological processes and signaling networks where the Krt9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- perinuclear region
- lysosome
- cytosol
- keratin intermediate filaments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Krt9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial cell differentiation
- spermatogenesis
- epidermis development
- skin development
- intermediate filament organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular space
- extracellular vesicular exosome
- keratin filament
- cytoskeleton
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- structural constituent of cytoskeleton