Krt9 Gene Summary [Rat]
Predicted to be a structural constituent of cytoskeleton. Involved in spermatogenesis. Located in keratin filament and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in epidermolytic palmoplantar keratoderma 1. Orthologous to human KRT9 (keratin 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Krt9 |
| Official Name | keratin 9 [Source:RGD Symbol;Acc:628785] |
| Ensembl ID | ENSRNOG00000014370 |
| Bio databases IDs | |
| Aliases | keratin 9 |
| Synonyms | CK-9, EPPK, EPPK1, K9, keratin 9, KRT1-9 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Krt9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of cytoskeleton
- Intermediate filament protein
Pathways
Biological processes and signaling networks where the Krt9 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- perinuclear region
- lysosome
- cytosol
- keratin intermediate filaments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Krt9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial cell differentiation
- spermatogenesis
- epidermis development
- skin development
- intermediate filament organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular space
- extracellular vesicular exosome
- keratin filament
- cytoskeleton
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- structural constituent of cytoskeleton