Kcnf1 Gene Summary [Mouse]
Predicted to enable potassium channel regulator activity. Involved in non-motile cilium assembly. Is active in ciliary base. Is expressed in several structures, including adipose tissue; bone; heart; lung; and spleen. Orthologous to human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kcnf1 |
| Official Name | potassium voltage-gated channel, subfamily F, member 1 [Source:MGI Symbol;Acc:MGI:2687399] |
| Ensembl ID | ENSMUSG00000051726 |
| Bio databases IDs | |
| Aliases | potassium voltage-gated channel, subfamily F, member 1 |
| Synonyms | Gm1182, IK8, KCNF, Kh1, KV5.1, potassium voltage-gated channel modifier subfamily F member 1, potassium voltage-gated channel, subfamily F, member 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kcnf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ion transport protein
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- potassium channel regulator
- protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kcnf1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transport
- potassium ion transmembrane transport
- protein homooligomerization
- regulation of action potential
Cellular Component
Where in the cell the gene product is active
- voltage-gated potassium channel complex
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- voltage-gated potassium channel activity
- protein binding
- potassium channel activity