Kcnf1 Gene Summary [Rat]

Enables potassium channel regulator activity. Involved in potassium ion transport and regulation of potassium ion transport. Part of voltage-gated potassium channel complex. Orthologous to human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Kcnf1
Official Name
potassium voltage-gated channel modifier subfamily F member 1 [Source:RGD Symbol;Acc:631414]
Ensembl ID
ENSRNOG00000024310
Bio databases IDs NCBI: 298908 Ensembl: ENSRNOG00000024310
Aliases potassium voltage-gated channel modifier subfamily F member 1
Synonyms Gm1182, IK8, KCNF, Kh1, KV5.1, potassium voltage-gated channel modifier subfamily F member 1, potassium voltage-gated channel, subfamily F, member 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kcnf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ion transport protein
  • Broad-Complex, Tramtrack and Bric a brac
  • BTB_POZ
  • potassium channel regulator
  • protein binding
  • ion channel

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Moyamoya disease
regulated by
regulates
  • K+
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Kcnf1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • potassium ion transport
  • potassium ion transmembrane transport
  • protein homooligomerization
  • regulation of action potential

Cellular Component

Where in the cell the gene product is active
  • voltage-gated potassium channel complex
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • voltage-gated potassium channel activity
  • protein binding
  • potassium channel activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.