Arhgef33 Gene Summary [Mouse]

Predicted to enable guanyl-nucleotide exchange factor activity. Orthologous to human ARHGEF33 (Rho guanine nucleotide exchange factor 33). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Arhgef33
Official Name
Rho guanine nucleotide exchange factor (GEF) 33 [Source:MGI Symbol;Acc:MGI:2685787]
Ensembl ID
ENSMUSG00000054901
Bio databases IDs NCBI: 381112 Ensembl: ENSMUSG00000054901
Aliases Rho guanine nucleotide exchange factor (GEF) 33
Synonyms Gm941, RGD1560224, Rho guanine nucleotide exchange factor 33
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arhgef33 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RhoGEF
  • RhoGEF domain

Pathways

Biological processes and signaling networks where the Arhgef33 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
disease
  • acute myeloid leukemia

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Arhgef33 gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • guanyl-nucleotide exchange factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.