Ces1d

Enables carboxylesterase activity; sterol ester esterase activity; and triacylglycerol lipase activity. Involved in acylglycerol catabolic process. Acts upstream of or within several processes, including circadian temperature homeostasis; cold-induced thermogenesis; and lipid catabolic process. Located in cytosol; endoplasmic reticulum lumen; and lipid droplet. Is expressed in several structures, including cochlear duct; gut; liver; nose; and respiratory system. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to several human genes including CES1 (carboxylesterase 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ces1d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ces1d gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.