Cfhr1 Gene Summary [Mouse]
Predicted to enable complement component C3b binding activity and identical protein binding activity. Predicted to be involved in complement activation. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in acute myeloid leukemia; age related macular degeneration 1; atypical hemolytic-uremic syndrome; and multiple myeloma. Orthologous to several human genes including CFHR1 (complement factor H related 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cfhr1 |
| Official Name | complement factor H-related 1 [Source:MGI Symbol;Acc:MGI:2138169] |
| Ensembl ID | ENSMUSG00000057037 |
| Bio databases IDs | |
| Aliases | complement factor H-related 1 |
| Synonyms | Cfhl1, Cfhr1-ps1, CFHRB, Comp fctr h-like 1, complement factor H-related 1, complement factor H-related 1, pseudogene 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cfhr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCP
- Sushi repeat (SCR repeat)
- identical protein binding
- SUSHI repeat
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface