Wdr83os Gene Summary [Mouse]

Predicted to enable protein folding chaperone. Predicted to be involved in multi-pass transmembrane protein insertion into ER membrane. Predicted to be part of multi-pass translocon complex and protein folding chaperone complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including brain and retina nuclear layer. Orthologous to human WDR83OS (WD repeat domain 83 opposite strand). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Wdr83os
Official Name
WD repeat domain 83 opposite strand [Source:MGI Symbol;Acc:MGI:3041257]
Ensembl ID
ENSMUSG00000059355
Bio databases IDs NCBI: 414077 Ensembl: ENSMUSG00000059355
Aliases WD repeat domain 83 opposite strand
Synonyms ASTERIX, BC056474, C19orf56, NEDFHCA, PAT-10, PTD008, RGD1564058, WD repeat domain 83 opposite strand
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr83os often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PAT complex subunit Asterix
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neurodevelopmental disorder with variable familial hypercholanemia
regulated by
regulates
role in cell
  • cell viability

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr83os gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein insertion into ER membrane
  • protein folding

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding involved in protein folding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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