Tmem208 Gene Summary [Mouse]
Predicted to be involved in vacuolar protein processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including adrenal gland; genitourinary system; liver; lung; and spleen. Orthologous to human TMEM208 (transmembrane protein 208). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem208 |
| Official Name | transmembrane protein 208 [Source:MGI Symbol;Acc:MGI:1913570] |
| Ensembl ID | ENSMUSG00000014856 |
| Bio databases IDs | |
| Aliases | transmembrane protein 208 |
| Synonyms | 1700006C06Rik, 2610030K20Rik, hSND2, HSPC171, RGD1560953, SND2, transmembrane protein 208 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem208 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SRP-independent targeting protein 2/TMEM208
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem208 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vacuolar protein processing
- autophagy
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- vacuole
Molecular Function
What the gene product does at the molecular level
- protein binding