Caln1 Gene Summary [Mouse]
Predicted to enable calcium ion binding activity. Located in trans-Golgi network membrane. Is expressed in central nervous system and retina. Orthologous to human CALN1 (calneuron 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Caln1 |
| Official Name | calneuron 1 [Source:MGI Symbol;Acc:MGI:2155987] |
| Ensembl ID | ENSMUSG00000060371 |
| Bio databases IDs | |
| Aliases | calneuron 1 |
| Synonyms | 9630012C17Rik, CABP8, calneuron 1, MNCb-0849 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Caln1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF-hand domain
- EF-hand domain pair
- EF hand
- calcium ion binding
- EFh
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
- Ca2+
- aldosterone
disease
- adenoma formation
- schizophrenia
- metabolic syndrome X
- pervasive developmental disorder
- progression free survival
- idiopathic scoliosis
- acne
- aldosterone producing adrenocortical adenoma
- refractive error
- corneal astigmatism
role in cell
- production in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- trans Golgi network
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Caln1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- trans-Golgi network membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding