Tmsb15a Gene Summary [Mouse]
Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration. Predicted to be active in cytoplasm. Is expressed in several structures, including heart; liver; lung; metanephros; and spleen. Orthologous to human TMSB15A (thymosin beta 15A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmsb15a |
| Official Name | thymosin beta 15a [Source:MGI Symbol;Acc:MGI:1925728] |
| Ensembl ID | ENSMUSG00000060726 |
| Bio databases IDs | |
| Aliases | thymosin beta 15a |
| Synonyms | 1700129I15Rik, NB THYMOSIN beta, NB THYMOSIN β, Tb15, Tb15a, TbNB, thymosin beta 15A, THYMOSIN beta (IDENTIFIED IN NEUROBLASTOMA), thymosin β 15A, THYMOSIN β (IDENTIFIED IN NEUROBLASTOMA), TMSB15, TMSB15B, Tmsbl1, TMSL8, TMSNB |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmsb15a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WH2
- Thymosin beta-4 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmsb15a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sequestering of actin monomers
- actin filament organization
- regulation of cell migration
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- actin monomer binding