Etnk2 Gene Summary [Mouse]
Enables ethanolamine kinase activity. Involved in phosphorylation. Acts upstream of or within several processes, including in utero embryonic development; phosphatidylethanolamine biosynthetic process; and placenta development. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; heart; intestine; liver; and lung. Orthologous to human ETNK2 (ethanolamine kinase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Etnk2 |
| Official Name | ethanolamine kinase 2 [Source:MGI Symbol;Acc:MGI:2443760] |
| Ensembl ID | ENSMUSG00000070644 |
| Bio databases IDs | |
| Aliases | ethanolamine kinase 2 |
| Synonyms | 4933417N20RIK, EKI 2, ethanolamine kinase 2, FLJ10761, HMFT1716, LOC100044148, Tuc1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Etnk2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Protein Kinases, catalytic domain
- Phosphotransferase enzyme family
- ethanolamine kinase
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Etnk2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- multicellular organism growth
- phosphatidylethanolamine biosynthetic process
- in utero embryonic development
- post-embryonic development
- phosphorylation
- placenta development
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- ethanolamine kinase activity
- protein binding