Etnk2 Gene Summary [Rat]

Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process and phosphorylation. Predicted to act upstream of or within in utero embryonic development; placenta development; and post-embryonic development. Predicted to be active in cytoplasm. Orthologous to human ETNK2 (ethanolamine kinase 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Etnk2
Official Name
ethanolamine kinase 2 [Source:RGD Symbol;Acc:1305304]
Ensembl ID
ENSRNOG00000028368
Bio databases IDs NCBI: 360843 Ensembl: ENSRNOG00000028368
Aliases ethanolamine kinase 2
Synonyms 4933417N20RIK, EKI 2, ethanolamine kinase 2, FLJ10761, HMFT1716, LOC100044148, Tuc1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Etnk2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • Protein Kinases, catalytic domain
  • Phosphotransferase enzyme family
  • ethanolamine kinase
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
  • oral submucous fibrosis
  • periodontitis
regulated by
regulates
  • phosphatidylethanolamine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Etnk2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • multicellular organism growth
  • phosphatidylethanolamine biosynthetic process
  • in utero embryonic development
  • post-embryonic development
  • phosphorylation
  • placenta development

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • ethanolamine kinase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

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