Npw Gene Summary [Mouse]
Orthologs of this gene express a preproprotein that is processed into a neuropeptide ligand for two G-protein coupled receptors in the central nervous system. The neuropeptide is thought to directly or indirectly regulate feeding, weight regulation, and pain response. The preproprotein is translated using a non-AUG initiation codon. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | Npw |
| Official Name | neuropeptide W [Source:MGI Symbol;Acc:MGI:2685781] |
| Ensembl ID | ENSMUSG00000071230 |
| Bio databases IDs | |
| Aliases | neuropeptide W |
| Synonyms | Gm935, L8, LOC259224, neuropeptide W, PPL8, PPNPW |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Npw often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Neuropeptides B and W
- G-protein-coupled receptor binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- perikaryon
- axon terminals
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Npw gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- G-protein coupled receptor signaling pathway
- feeding behavior
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor binding
- protein binding