Hspa13 Gene Summary [Mouse]
Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein refolding. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol; nucleus; and plasma membrane. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human HSPA13 (heat shock protein family A (Hsp70) member 13). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Hspa13 |
| Official Name | heat shock protein 70 family, member 13 [Source:MGI Symbol;Acc:MGI:1309463] |
| Ensembl ID | ENSMUSG00000032932 |
| Bio databases IDs | |
| Aliases | heat shock protein 70 family, member 13 |
| Synonyms | 1600002I10Rik, B230217N24Rik, heat shock protein 70 family, member 13, heat shock protein family A (Hsp70) member 13, STCH, STRESS 70 protein CHAPERONE |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hspa13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATPase domain
- protein binding
- ASKHA_ATPase-like
Pathways
Biological processes and signaling networks where the Hspa13 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Mitochondria
- microsome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hspa13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chaperone mediated protein folding requiring cofactor
- protein refolding
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytoplasm
- intracellular membrane-bounded organelle
- cytosol
- endoplasmic reticulum
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- heat shock protein binding
- protein binding
- protein binding involved in protein folding