Gspt2 Gene Summary [Mouse]
Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in translational termination. Predicted to be located in cytoplasm. Predicted to be part of translation release factor complex. Is expressed in adrenal gland; central nervous system; genitourinary system; and intestine. Orthologous to human GSPT2 (G1 to S phase transition 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gspt2 |
| Official Name | G1 to S phase transition 2 [Source:MGI Symbol;Acc:MGI:1316727] |
| Ensembl ID | ENSMUSG00000071723 |
| Bio databases IDs | |
| Aliases | G1 to S phase transition 2 |
| Synonyms | eRF3b, G1 to S phase transition 2, RGD1563213 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gspt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain III of Elongation factor (EF) Tu (EF-TU) and related proteins
- Domain II of Elongation factor Tu (EF-Tu)-like proteins
- sulfate adenylyltransferase, large subunit
- small GTP-binding protein domain
- Ataxin-2 C-terminal region
- Elongation factor Tu C-terminal domain
- GTPase
- Elongation factor Tu GTP binding domain
- Elongation factor Tu domain 2
- translation release factor
- P-loop containing Nucleoside Triphosphate Hydrolases
- translation regulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown