Cfap47 Gene Summary [Mouse]
Involved in sperm axoneme assembly. Located in sperm head-tail coupling apparatus. Used to study male infertility. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 3. Orthologous to human CFAP47 (cilia and flagella associated protein 47). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cfap47 |
| Official Name | cilia and flagella associated protein 47 [Source:MGI Symbol;Acc:MGI:3781475] |
| Ensembl ID | ENSMUSG00000073077 |
| Bio databases IDs | |
| Aliases | cilia and flagella associated protein 47 |
| Synonyms | CHDC2, cilia and flagella associated protein 47, CXorf22, CXorf30, CXorf59, Gm16462, Gm3297, Gm7173, Gm8787, LOC101928564, LOC101928593, LOC682070, RGD1560207, SPGF52, SPGFX3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cfap47 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calponin homology domain
- calponin homology (CH) domain superfamily
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cfap47 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- sperm axoneme assembly
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
- cilium
Molecular Function
What the gene product does at the molecular level
- protein binding