Arhgap40 Gene Summary [Mouse]
Predicted to enable GTPase activator activity. Predicted to be involved in regulation of actin filament polymerization and regulation of small GTPase mediated signal transduction. Predicted to be active in cytoplasm. Is expressed in testis. Orthologous to human ARHGAP40 (Rho GTPase activating protein 40). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Arhgap40 |
| Official Name | Rho GTPase activating protein 40 [Source:MGI Symbol;Acc:MGI:3649852] |
| Ensembl ID | ENSMUSG00000074625 |
| Bio databases IDs | |
| Aliases | Rho GTPase activating protein 40 |
| Synonyms | C20orf95, dJ1100H13.4, Gm14203, RGD1562428, Rho GTPase activating protein 40 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arhgap40 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RhoGAP domain
- GTPase activator
- GTPase-activator protein for Rho-like GTPases
- RhoGAP
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Arhgap40 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of actin filament polymerization
- regulation of small GTPase mediated signal transduction
- signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- GTPase activator activity