Capns2 Gene Summary [Mouse]

Predicted to enable calcium ion binding activity and calcium-dependent cysteine-type endopeptidase activity. Predicted to be located in plasma membrane. Predicted to be part of calpain complex. Orthologous to human CAPNS2 (calpain small subunit 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Capns2
Official Name
calpain, small subunit 2 [Source:MGI Symbol;Acc:MGI:1916793]
Ensembl ID
ENSMUSG00000078144
Bio databases IDs NCBI: 69543 Ensembl: ENSMUSG00000078144
Aliases calpain, small subunit 2
Synonyms 2310005G05Rik, 30K-2, calpain small subunit 2, calpain, small subunit 2, CSS2, LOC682500
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Capns2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • The penta-EF hand (PEF) family
  • calpain
  • EF-hand domain pair
  • peptidase
  • EFh
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Capns2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding
  • calcium-dependent cysteine-type endopeptidase activity