Srp72 Gene Summary [Mouse]
Predicted to enable 7S RNA binding activity; TPR domain binding activity; and signal recognition particle binding activity. Predicted to contribute to ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum and nucleolus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Orthologous to human SRP72 (signal recognition particle 72). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Srp72 |
| Official Name | signal recognition particle 72 [Source:MGI Symbol;Acc:MGI:1333795] |
| Ensembl ID | ENSMUSG00000036323 |
| Bio databases IDs | |
| Aliases | signal recognition particle 72 |
| Synonyms | 5730576P14Rik, BC019196, BMFF, BMFS1, HEL103, LOC100910272, LOC108348046, signal recognition particle 72 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Srp72 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- 7S RNA binding
- signal recognition particle binding
- Putative TPR-like repeat
- ribosome binding
- protein domain specific binding
- protein binding
- SRP72 RNA-binding domain
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
- cytosol
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Srp72 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- SRP-dependent cotranslational protein targeting to membrane
Cellular Component
Where in the cell the gene product is active
- signal recognition particle
- cytosol
- endoplasmic reticulum
- signal recognition particle, endoplasmic reticulum targeting
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- TPR domain binding
- ribosome binding
- 7S RNA binding
- signal recognition particle binding