Sult2a5 Gene Summary [Mouse]

Predicted to enable 3'-phosphoadenosine 5'-phosphosulfate binding activity and sulfotransferase activity. Predicted to be involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; ethanol catabolic process; and sulfation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sult2a5
Official Name
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5 [Source:MGI Symbol;Acc:MGI:3648378]
Ensembl ID
ENSMUSG00000078799
Bio databases IDs NCBI: 434264 Ensembl: ENSMUSG00000078799
Aliases sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
Synonyms BAST I, DST, EG434121, EG434264, EG629219, Gm15438, Gm5584, Gm6955, Gm6957, Hsta, Hydroxysteroid Sulfotransferase, Hydroxysteroid sulphotransferase, LOC100360672, LOC100364224, mSTa1, RATSMP2A, RATSMP2B, SMP-2, Smp2a, St2, ST2A1, ST2A2, ST2A6, ST-41, STa, Std, Sth1, Sth2, Sulfotransferase family, 2a1, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6, sulfotransferase family 2A member 1, Sulfotransferase hydroxysteroid gene 2, sulphotransferase family, 2a1, sulphotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1, sulphotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2, sulphotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3, sulphotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4, sulphotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5, sulphotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6, sulphotransferase family 2A member 1, sulphotransferase hydroxysteroid gene 2, Sult2-40/41, Sult2a2, Sult2a3, Sult2a4, Sult2a-40/41, Sult2a4l1, Sult2a5, Sult2a6, Sult2a9, Sult2al1
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sult2a5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • bile-salt sulfotransferase
  • sulfotransferase
  • steroid sulfotransferase
  • transferase
  • Sulfotransferase domain
  • alcohol sulfotransferase
  • enzyme
  • 3'-phosphoadenosine 5'-phosphosulfate binding
  • Sulfotransferase family

Pathways

Biological processes and signaling networks where the Sult2a5 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • cisplatin
  • ABCC4
  • JUN
  • hydrocortisone
  • AR
  • pregnenolone carbonitrile
  • calcitriol
  • vitamin D
  • VDR
  • lithocholic acid
regulates
  • thymidine kinase
  • Sult2a1 (includes others)
  • steroid
  • xenobiotic
role in cell
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.