Gnasas1 Gene Summary [Mouse]
Acts upstream of or within several processes, including genomic imprinting; skin development; and tissue homeostasis. Is expressed in several structures, including brain; limb; and somite. Used to study pseudohypoparathyroidism. Human ortholog(s) of this gene implicated in pseudohypoparathyroidism type 1B. Orthologous to human GNAS-AS1 (GNAS antisense RNA 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | Gnasas1 |
| Official Name | GNAS antisense RNA 1 [Source:MGI Symbol;Acc:MGI:1861674] |
| Ensembl ID | ENSMUSG00000086537 |
| Bio databases IDs | |
| Aliases | GNAS antisense RNA 1 |
| Synonyms | GNAS antisense RNA 1, Nespas, Nespos |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gnasas1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- growth failure
- hyperactive behavior
- mitochondrial disorder
- edema
role in cell
- expression in
- depolarization in
- depolarization
- dysfunction in
- dysfunction
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown