Abhd12b Gene Summary [Mouse]
Predicted to enable lysophospholipase activity and monoacylglycerol lipase activity. Predicted to be involved in monoacylglycerol catabolic process and phosphatidylserine catabolic process. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ABHD12B (abhydrolase domain containing 12B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Retained Intron |
| Official Symbol | Abhd12b |
| Official Name | abhydrolase domain containing 12B [Source:MGI Symbol;Acc:MGI:2685650] |
| Ensembl ID | ENSMUSG00000090121 |
| Bio databases IDs | |
| Aliases | abhydrolase domain containing 12B |
| Synonyms | abhydrolase domain containing 12B, BEM46L3, c14 5314, C14orf29, Gm804 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Abhd12b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Prolyl oligopeptidase family
- alpha/beta hydrolase fold
- alpha/beta hydrolases
- Serine aminopeptidase, S33
- Alpha/beta hydrolase family
- peptidase
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Abhd12b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- monoacylglycerol catabolic process
- phosphatidylserine catabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- lysophospholipase activity
- acylglycerol lipase activity