Serpinb10 Gene Summary [Mouse]
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of proteolysis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in extracellular space. Is expressed in several structures, including esophagus; liver lobe; oral epithelium; and skin. Orthologous to human SERPINB10 (serpin family B member 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Serpinb10 |
| Official Name | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10 [Source:MGI Symbol;Acc:MGI:2138648] |
| Ensembl ID | ENSMUSG00000092572 |
| Bio databases IDs | |
| Aliases | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10 |
| Synonyms | 9830131G07, PI-10, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10, Serpinb10-ps, serpin family B member 10, Trespin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Serpinb10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SERine Proteinase INhibitors (serpin) family
- protease inhibitor
- serine protease inhibitor activity
- Serpin (serine protease inhibitor)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Plasma Membrane
- secretory granule membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Serpinb10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of endopeptidase activity
Cellular Component
Where in the cell the gene product is active
- secretory granule membrane
- extracellular space
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase inhibitor activity