Serpinb10 Gene Summary [Rat]

Enables peptidase inhibitor activity. Involved in negative regulation of proteolysis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in extracellular space. Orthologous to human SERPINB10 (serpin family B member 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Serpinb10
Official Name
serpin family B member 10 [Source:RGD Symbol;Acc:628853]
Ensembl ID
ENSRNOG00000002417
Bio databases IDs NCBI: 266775 Ensembl: ENSRNOG00000002417
Aliases serpin family B member 10
Synonyms 9830131G07, PI-10, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10, Serpinb10-ps, serpin family B member 10, Trespin
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Serpinb10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SERine Proteinase INhibitors (serpin) family
  • protease inhibitor
  • serine protease inhibitor activity
  • Serpin (serine protease inhibitor)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • localized cutaneous leishmaniasis
regulated by
  • TGFB1
  • TNF
  • LR3 IGF-I
  • SRF
  • cycloheximide
  • MRTFA
  • MRTFB
  • NEF
  • tetradecanoylphorbol acetate
  • lorlatinib
regulates
role in cell
  • cell death

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • Plasma Membrane
  • secretory granule membrane
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Serpinb10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of endopeptidase activity

Cellular Component

Where in the cell the gene product is active
  • secretory granule membrane
  • extracellular space
  • cytosol
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • serine-type endopeptidase inhibitor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.