Jpx Gene Summary [Mouse]
Acts upstream of or within gene expression and positive regulation of transcription by RNA polymerase II. Orthologous to human JPX (JPX transcript, XIST activator). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | Jpx |
| Official Name | Jpx transcript, Xist activator (non-protein coding) [Source:MGI Symbol;Acc:MGI:2180008] |
| Ensembl ID | ENSMUSG00000097571 |
| Bio databases IDs | |
| Aliases | Jpx transcript, Xist activator (non-protein coding) |
| Synonyms | 2010000I03Rik, 2510040I06RIK, DCBALD06, ENOX, JPX transcript, XIST activator, Jpx transcript, Xist activator (non-protein coding), LINC00183, NCRNA00183 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Jpx often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- double-stranded DNA binding
- sequence-specific DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- epithelial cancer
- cancer
- Turner syndrome
- liver cancer
- Klinefelter syndrome
- liver neoplasia
- digestive system cancer
- abdominal cancer
- epithelial neoplasia
role in cell
- expression in
- proliferation
- migration
- transactivation in
- apoptosis
- cell proliferation
- inactivation
- invasion by
- inactivation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Jpx gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription from RNA polymerase II promoter