Jmjd7 Gene Summary [Mouse]

Predicted to enable several functions, including methylated histone binding activity; peptidase activity; and peptidyl-lysine 3-dioxygenase activity. Predicted to be involved in protein hydroxylation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in alimentary system; axial skeleton; nervous system; respiratory system; and urinary system. Orthologous to human JMJD7 (jumonji domain containing 7). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Jmjd7
Official Name
jumonji domain containing 7 [Source:MGI Symbol;Acc:MGI:3845785]
Ensembl ID
ENSMUSG00000098789
Bio databases IDs NCBI: 433466 Ensembl: ENSMUSG00000098789
Aliases jumonji domain containing 7
Synonyms jumonji domain containing 7, LOC100131005
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Jmjd7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • histone binding
  • endopeptidase
  • 2-oxoglutarate:oxygen oxidoreductase
  • peptidase
  • aminopeptidase
  • monooxygenase
  • enzyme
  • protein binding
  • RmlC-like cupin superfamily
  • Cupin-like domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Jmjd7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis
  • protein hydroxylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • methylated histone residue binding
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
  • endopeptidase activity
  • aminopeptidase activity
  • monooxygenase activity

Gene-Specific Assays for Results You Can Trust

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