Ldhal6b Gene Summary [Mouse]

Predicted to enable L-lactate dehydrogenase activity. Predicted to be involved in lactate metabolic process. Located in mitochondrion. Orthologous to several human genes including LDHAL6B (lactate dehydrogenase A like 6B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ldhal6b
Official Name
lactate dehydrogenase A-like 6B [Source:MGI Symbol;Acc:MGI:2146830]
Ensembl ID
ENSMUSG00000101959
Bio databases IDs NCBI: 106557 Ensembl: ENSMUSG00000101959
Aliases lactate dehydrogenase A-like 6B
Synonyms 4933402O15Rik, lactate dehydrogenase A-like 6B, LDH6B, Ldha16b, Ldhal, LDHAL6, LDHL
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ldhal6b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rossmann-fold NAD(P)(+)-binding proteins
  • L-lactate dehydrogenase
  • lactate/malate dehydrogenase, NAD binding domain
  • enzyme
  • protein binding
  • lactate/malate dehydrogenase, alpha/beta C-terminal domain
  • malate dehydrogenase, NAD-dependent

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • lactic acid
  • pyruvic acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • mitochondrial matrix
  • cytoplasmic droplets

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ldhal6b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • lactate metabolic process
  • pyruvate metabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • mitochondrial matrix
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • L-lactate dehydrogenase activity