Snrpc Gene Summary [Rat]
Enables U1 snRNP binding activity. Predicted to be involved in mRNA 5'-splice site recognition and spliceosomal snRNP assembly. Part of U1 snRNP. Human ortholog(s) of this gene implicated in connective tissue disease; mixed connective tissue disease; and systemic lupus erythematosus. Orthologous to human SNRPC (small nuclear ribonucleoprotein polypeptide C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snrpc |
| Official Name | small nuclear ribonucleoprotein polypeptide C [Source:RGD Symbol;Acc:1306065] |
| Ensembl ID | ENSRNOG00000000493 |
| Bio databases IDs | |
| Aliases | small nuclear ribonucleoprotein polypeptide C |
| Synonyms | small nuclear ribonucleoprotein polypeptide C, snRNP C U1, SNRP1C, U1-C, U1 small nuclear ribonucleoprotein C, Yhc1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snrpc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- ribonucleoprotein binding
- protein homodimerization
- U1 zinc finger
- protein binding
- single-stranded RNA binding
Pathways
Biological processes and signaling networks where the Snrpc gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pain
- insomnia
- psoriasis
- peripheral neuropathy
- infection by HIV-1
regulates
- snRNP
- luciferase reporter gene
role in cell
- production in
- cell viability
- reverse transcription
- splicing by
- reverse transcription in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
- Cajal bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snrpc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA 5'-splice site recognition
- nuclear mRNA splicing, via spliceosome
- spliceosomal snRNP assembly
Cellular Component
Where in the cell the gene product is active
- commitment complex
- nucleus
- Cajal body
- spliceosomal complex
- U2-type prespliceosome
- U1 snRNP
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- RNA binding
- protein homodimerization activity
- pre-mRNA 5'-splice site binding
- U1 snRNA binding
- single-stranded RNA binding
- mRNA binding