Nudcd2 Gene Summary [Rat]

Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytosol; intercellular bridge; and mitotic spindle. Predicted to be active in cytoplasm. Orthologous to human NUDCD2 (NudC domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nudcd2
Official Name
NudC domain containing 2 [Source:RGD Symbol;Acc:1307203]
Ensembl ID
ENSRNOG00000060914
Bio databases IDs NCBI: 287199 Ensembl: ENSRNOG00000060914
Aliases NudC domain containing 2
Synonyms NudC domain containing 2, NudCL2, RGD1307203, RIKEN CDNA 2700047N05
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nudcd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CS domain
  • alpha-crystallin Hsps/p23-like
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • osteoporosis
  • rheumatoid arthritis
  • nonalcoholic fatty liver disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microtubule cytoskeleton
  • cytoplasmic bridges
  • cytosol
  • mitotic spindle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nudcd2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein folding

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • intercellular bridge
  • microtubule cytoskeleton
  • mitotic spindle
  • cytoplasm
  • spindle pole
  • cytosol
  • kinetochore

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • unfolded protein binding

Gene-Specific Assays for Results You Can Trust

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