Armc12 Gene Summary [Rat]

Predicted to be involved in positive regulation of cell growth and sperm mitochondrial sheath assembly. Predicted to be located in mitochondrial outer membrane. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in spermatogenic failure 90. Orthologous to human ARMC12 (armadillo repeat containing 12). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Armc12
Official Name
armadillo repeat containing 12 [Source:RGD Symbol;Acc:1306008]
Ensembl ID
ENSRNOG00000000508
Bio databases IDs NCBI: 294301 Ensembl: ENSRNOG00000000508
Aliases armadillo repeat containing 12
Synonyms 4930511I11Rik, armadillo repeat containing 12, C6orf81, FLJ25390, RGD1306008, SPGF90
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Armc12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Armadillo-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • spermatogenic failure 90
  • diabetic nephropathy
role in cell
  • growth
  • adhesion
  • motility
  • elongation
  • elongation in
  • adhesion in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Plasma Membrane
  • Mitochondria
  • mitochondrial outer membrane
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Armc12 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of cell growth
  • sperm motility

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • mitochondrial outer membrane
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.