Armc12 Gene Summary [Mouse]
Involved in sperm mitochondrial sheath assembly. Located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in spermatogenic failure 90. Orthologous to human ARMC12 (armadillo repeat containing 12). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Armc12 |
| Official Name | armadillo repeat containing 12 [Source:MGI Symbol;Acc:MGI:1914895] |
| Ensembl ID | ENSMUSG00000024223 |
| Bio databases IDs | |
| Aliases | armadillo repeat containing 12 |
| Synonyms | 4930511I11Rik, armadillo repeat containing 12, C6orf81, FLJ25390, RGD1306008, SPGF90 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Armc12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Armadillo-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- Mitochondria
- mitochondrial outer membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Armc12 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of cell growth
- sperm motility
Cellular Component
Where in the cell the gene product is active
- nucleus
- mitochondrial outer membrane
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding