Efhd1 Gene Summary [Rat]
Predicted to enable calcium ion binding activity and calcium ion sensor activity. Predicted to be involved in regulation of cellular hyperosmotic salinity response. Predicted to act upstream of or within neuron projection development. Predicted to be active in mitochondrial inner membrane. Orthologous to human EFHD1 (EF-hand domain family member D1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Efhd1 |
| Official Name | EF-hand domain family, member D1 [Source:RGD Symbol;Acc:1559565] |
| Ensembl ID | ENSRNOG00000015596 |
| Bio databases IDs | |
| Aliases | EF-hand domain family, member D1 |
| Synonyms | 4931430I01RIK, EF hand domain containing 1, EF-hand domain family member D1, EF-hand domain family, member D1, mitocalcin, MST133, MSTP133, PP3051, RGD1559565, Swiprosin 2, SWS2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Efhd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF-hand domain
- EF hand
- EF-hand domain pair
- EF-hand, calcium binding motif, found in parvalbumin-like EF-hand family
- EFh
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Efhd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuron projection development
- regulation of cellular hyperosmotic salinity response
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding