Btbd9 Gene Summary [Rat]
Predicted to be involved in adult locomotory behavior; circadian behavior; and modulation of chemical synaptic transmission. Predicted to act upstream of or within several processes, including circadian sleep/wake cycle, non-REM sleep; long-term memory; and multicellular organismal-level iron ion homeostasis. Predicted to be active in cytoplasm and glutamatergic synapse. Orthologous to human BTBD9 (BTB domain containing 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Btbd9 |
| Official Name | BTB domain containing 9 [Source:RGD Symbol;Acc:1306975] |
| Ensembl ID | ENSRNOG00000000540 |
| Bio databases IDs | |
| Aliases | BTB domain containing 9 |
| Synonyms | 1700023F20RIK, 4930402L05, BTB domain containing 9, dJ322I12.1, LOC100361081, LOC100362201 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Btbd9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BTB And C-terminal Kelch
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- F5/8 type C domain
- BTB/POZ domain
- protein binding
- BACK (BTB and C-terminal Kelch) domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- metabolic syndrome X
- lung squamous cell carcinoma
- insomnia
- restless legs syndrome
- acute myeloid leukemia
- colorectal cancer
- squamous cell lung cancer
- sleep disorder
- periodic limb movement disorder
regulates
- 5-hydroxytryptamine
- dopamine
role in cell
- growth
- abnormal morphology
- paired-pulse facilitation
- plasticity
- endocytosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- glutaminergic synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Btbd9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- long-term memory
- serotonin metabolic process
- circadian sleep/wake cycle, non-REM sleep
- multicellular organismal iron ion homeostasis
- regulation of synaptic vesicle endocytosis
- regulation of synaptic transmission
- adult locomotory behavior
- circadian behavior
- sensory perception of temperature stimulus
Cellular Component
Where in the cell the gene product is active
- cytoplasm