Gpn3 Gene Summary [Rat]

Predicted to enable GTPase activity. Predicted to be part of protein-containing complex. Orthologous to human GPN3 (GPN-loop GTPase 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gpn3
Official Name
GPN-loop GTPase 3 [Source:RGD Symbol;Acc:1303034]
Ensembl ID
ENSRNOG00000001278
Bio databases IDs NCBI: 360810 Ensembl: ENSRNOG00000001278
Aliases GPN-loop GTPase 3
Synonyms A930018B01Rik, ATPBD1C, D5Ertd708e, GPN-loop GTPase 3, MGC14560, PARCS
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gpn3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • Conserved hypothetical ATP binding protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • nonalcoholic fatty liver disease
regulates
role in cell
  • proliferation
  • early G1 phase
  • accumulation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gpn3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • macromolecular complex

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.