Naa25 Gene Summary [Rat]

Predicted to enable acetyltransferase activator activity. Predicted to be involved in cytoskeleton organization. Located in cytoplasm. Orthologous to human NAA25 (N-alpha-acetyltransferase 25, NatB auxiliary subunit). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Naa25
Official Name
N(alpha)-acetyltransferase 25, NatB auxiliary subunit [Source:RGD Symbol;Acc:1305685]
Ensembl ID
ENSRNOG00000001350
Bio databases IDs NCBI: 360811 Ensembl: ENSRNOG00000001350
Aliases N(alpha)-acetyltransferase 25, NatB auxiliary subunit
Synonyms 4833422K13Rik, A630046C11, AI450868, C12orf30, C330023M02Rik, FLJ13089, LRRGT00164, MDM20, N-alpha-acetyltransferase 25, NatB auxiliary subunit, N(alpha)-acetyltransferase 25, NatB auxiliary subunit, NAP1, N-α-acetyltransferase 25, NatB auxiliary subunit, N(α)-acetyltransferase 25, NatB auxiliary subunit, RGD1305685
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Naa25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • N-acetyltransferase B complex (NatB) non catalytic subunit
  • protein binding
  • tetratricopeptide repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • stroke
  • major depression
  • colorectal cancer
  • breast carcinoma
  • coronary artery disease
  • non-small cell lung carcinoma
  • non-small cell lung cancer
  • gout
  • hypothyroidism
  • myocardial infarction
regulated by
  • RYR1
  • Ebna-LP
  • B lymphocytes
  • Ebna2
role in cell
  • migration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Naa25 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • N-terminal peptidyl-methionine acetylation

Cellular Component

Where in the cell the gene product is active
  • NatB complex
  • cytoplasm
  • cytosol
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.