Cyp3a62 Gene Summary [Rat]

Predicted to enable testosterone 6-beta-hydroxylase activity. Predicted to be involved in oxidative demethylation and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in familial Mediterranean fever. Orthologous to human CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cyp3a62
Official Name
cytochrome P450, family 3, subfamily a, polypeptide 62 [Source:RGD Symbol;Acc:1595919]
Ensembl ID
ENSRNOG00000001379
Bio databases IDs NCBI: 170509 Ensembl: ENSRNOG00000001379
Aliases cytochrome P450, family 3, subfamily a, polypeptide 62
Synonyms CYP3, Cyp3a, Cyp3a62, CYP3A7, CYP3A7.1L, CYP3A7-3AP1, CYP3A7-CYP3A51P readthrough, CYP3A7-CYP3AP1, CYPIIIA7, cytochrome P450, family 3, subfamily a, polypeptide 62
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cyp3a62 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • cytochrome P450 (CYP) superfamily
  • Cytochrome P450
  • enzyme

Pathways

Biological processes and signaling networks where the Cyp3a62 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • lipopolysaccharide
  • MYC
  • dexamethasone
  • insulin
  • tretinoin
  • ethanol
  • L-742694
  • ketoconazole
  • Ro 48-8071
  • IL2
regulates
  • 7-benzyloxyquinoline
  • amiodarone
  • 7-quinolinol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microsomal fraction
  • microsome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.