Xxylt1 Gene Summary [Rat]
Predicted to enable magnesium ion binding activity; manganese ion binding activity; and xylosyl alpha-1,3-xylosyltransferase activity. Predicted to be involved in O-glycan processing. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human XXYLT1 (xyloside xylosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Xxylt1 |
| Official Name | xyloside xylosyltransferase 1 [Source:RGD Symbol;Acc:1308154] |
| Ensembl ID | ENSRNOG00000001729 |
| Bio databases IDs | |
| Aliases | xyloside xylosyltransferase 1 |
| Synonyms | C3orf21, RGD1308154, xyloside xylosyltransferase 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Xxylt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme
- protein binding
- xylosyltransferase
- UDP-glycosyltransferase
- manganese ion binding
- magnesium ion binding
- Glycosyl transferase family 8
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- venous thromboembolism
- atrial fibrillation
- non-insulin-dependent diabetes mellitus
- metabolic syndrome X
- non-small cell lung cancer
- non-small cell lung carcinoma
regulates
- NOTCH1
- O-glycan
role in cell
- xylosylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Xxylt1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- O-glycan processing
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- UDP-xylosyltransferase activity
- manganese ion binding