Slain2 Gene Summary [Rat]

Predicted to be involved in cytoplasmic microtubule organization; microtubule nucleation; and positive regulation of microtubule polymerization. Predicted to be located in centrosome and cytosol. Predicted to colocalize with microtubule plus-end. Orthologous to human SLAIN2 (SLAIN motif family member 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slain2
Official Name
SLAIN motif family, member 2 [Source:RGD Symbol;Acc:1311593]
Ensembl ID
ENSRNOG00000002271
Bio databases IDs NCBI: 305310 Ensembl: ENSRNOG00000002271
Aliases SLAIN motif family, member 2
Synonyms 5033405K12Rik, 8030444K12Rik, KIAA1458, RGD1311593, SLAI2, SLAIN motif family member 2, SLAIN motif family, member 2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slain2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SLAIN motif-containing family
  • protein binding
  • zDHHC ankyrin repeat binding domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • uterine leiomyoma
  • leiomyomatosis
  • Crohn disease
  • inflammatory bowel disease
regulated by
role in cell
  • growth
  • growth in
  • organization
  • catastrophe
  • catastrophe in
  • extension in
  • polymerization
  • extension
  • nucleation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microtubule cytoskeleton
  • centrosome
  • Mitochondria
  • microtubules
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Slain2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • microtubule nucleation
  • cytoplasmic microtubule organization
  • positive regulation of microtubule polymerization

Cellular Component

Where in the cell the gene product is active
  • microtubule cytoskeleton
  • centrosome
  • microtubule plus end
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.