SLAIN2 Gene Summary [Human]
Involved in cytoplasmic microtubule organization; microtubule nucleation; and positive regulation of microtubule polymerization. Located in centrosome and cytosol. Colocalizes with microtubule plus-end. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SLAIN2 |
| Official Name | SLAIN motif family member 2 [Source:HGNC Symbol;Acc:HGNC:29282] |
| Ensembl ID | ENSG00000109171 |
| Bio databases IDs | |
| Aliases | SLAIN motif family member 2 |
| Synonyms | 5033405K12Rik, 8030444K12Rik, KIAA1458, RGD1311593, SLAI2, SLAIN motif family member 2, SLAIN motif family, member 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLAIN2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SLAIN motif-containing family
- protein binding
- zDHHC ankyrin repeat binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- centrosome
- Mitochondria
- microtubules
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLAIN2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule nucleation
- cytoplasmic microtubule organization
- positive regulation of microtubule polymerization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- centrosome
- microtubule plus end
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding