Slain2 Gene Summary [Mouse]
Involved in cytoplasmic microtubule organization and regulation of microtubule polymerization. Predicted to be located in centrosome and cytosol. Predicted to colocalize with microtubule plus-end. Is expressed in several structures, including 1st branchial arch mandibular component; brain; liver lobe; and mandibular process. Orthologous to human SLAIN2 (SLAIN motif family member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slain2 |
| Official Name | SLAIN motif family, member 2 [Source:MGI Symbol;Acc:MGI:1923241] |
| Ensembl ID | ENSMUSG00000036087 |
| Bio databases IDs | |
| Aliases | SLAIN motif family, member 2 |
| Synonyms | 5033405K12Rik, 8030444K12Rik, KIAA1458, RGD1311593, SLAI2, SLAIN motif family member 2, SLAIN motif family, member 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slain2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SLAIN motif-containing family
- protein binding
- zDHHC ankyrin repeat binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- centrosome
- Mitochondria
- microtubules
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slain2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule nucleation
- cytoplasmic microtubule organization
- positive regulation of microtubule polymerization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- centrosome
- microtubule plus end
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding